Remap ctrl+alt+shift+win keyboard shortcut

I actually used this shortcut to quickly open Office.com at work. But now it redirects on my account to Copilot and… yeah I don’t need it everywhere.

So how do we remap it? I tried with PowerToys but it seems to be reserved for Windows. But I found a registry solution with a .reg file

Windows Registry Editor Version 5.00

[HKEY_CURRENT_USER\Software\Classes\ms-officeapp\Shell\Open\Command]
@="https://contoso.sharepoint.com/"

Replace YourURL or use rundll32 to deactivate it.